Endocrine Abstracts

Bariatric surgery is known to improve obesity-induced systemic inflammation and glucose homeostasis, however, the exact mechanisms behind this effect are not fully understood. We have previously shown that Sodium Glucose Transporter 2 (SGLT2) is significantly inhibited in the kidney cortex following Vertical Sleeve Gastrectomy (VSG), causing a reduction in renal glucose reabsorption. In this study, we hypothesize that the observed post-operative reduction of SGLT2 is controlle...